Splice: Directed by Vincenzo Natali. With Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon. Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.

Geneticists Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in creating hybrids of species. When they propose the use of human DNA, their pharmaceutical company bosses forbid it, forcing...

Genetic engineers Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) achieve fame by successfully splicing together the DNA of different animals to create incredible new hybrid animals. Now they want to use human DNA in a hybrid that could revolutionize science and medicine.

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Splice Brilliant geneticists cross moral, ethical and legal boundaries when they add human DNA to a new organism they have created. The result is Dren: a human-animal hybrid who quickly grows out of their control.

Superstar genetic engineers Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in splicing together DNA from different animals to create incredible new hybrids. Now they want to use human DNA...

Superstar genetic engineers Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in splicing DNA from different animals to create incredible new hybrids. ...

Produced by Guillermo del Toro, Splice stars Adrian Brody and Sarah Polley as a young scientist couple who, after introducing human DNA into their work with genetic splicing, create a human-animal hybrid being called Dren, who becomes like the couple's child.

Overview. Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism.